DETAILED NOTES ON LIMITED EDITION EXCLUSIVE LSD CRYSTAL)

In the LSD-bound crystal framework, the aspect chain of the lid residue L209EL2 varieties considerable hydrophobic contacts with both of those LSD and encompassing residues in TMs III, IV, and V (Determine 4C). When the lid moved aside to reveal the binding pocket in simulation, several of these contacts broke. We As a result hypothesized that L209